Factrel

Inquiry

Cat Number

API51952411

CAS Number

51952-41-1

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Product Detail Description Customer Q&A

CAS Number

51952-41-1

Synonyms

Gonadorelin HCl

Molecular Formula

C55H76ClN17O13

Molecular Weight

1218.7

Smiles

CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6.Cl

Appearance

Solid

General Description

Factrel, also known as gonadorelin hydrochloride, is a synthetic decapeptide gonadotropin-releasing hormone (GnRH) identical in structure to the naturally occurring hypothalamic peptide. It is formulated as the hydrochloride salt and consists of the sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2.

Mechanism of Action

Factrel binds to GnRH receptors on anterior pituitary gonadotroph cells, stimulating the synthesis and secretion of both luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This gonadotropin release stimulates gonadal steroidogenesis and gametogenesis within the hypothalamic-pituitary-gonadal axis.

Application

Indicated for the evaluation of hypothalamic-pituitary-gonadal function and in reproductive endocrinology diagnostics. Factrel is a synthetic GnRH identical to native hypothalamic hormone, used to assess pituitary reserve capacity and diagnose gonadotropin deficiency in infertility workups.

How does Factrel compare to synthetic GnRH superagonists?

Factrel is identical to native GnRH and stimulates an initial gonadotropin surge, whereas synthetic superagonist analogs are modified for enhanced potency and sustained receptor downregulation.

What purity grade is available?

Supplied as a high-purity grade suitable for peptide drug R&D and pharmaceutical manufacturing.

Can packaging be customized?

Packaging and order quantities can be customized to meet specific R&D and laboratory requirements.

Is international shipping available?

Available for shipment to customers across most countries and regions worldwide.