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Elexacaftor

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Cat Number

API2216712660

CAS Number

2216712-66-0

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Product Detail

CAS Number

2216712-66-0

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Elexacaftor (VX-445)is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It promotes the processing and trafficking of CFTR, increases the amount of CFTR on the cell surface, and improves the processing and trafficking of Phe508del CFTR protein.

Molecular Formula

C26H34F3N7O4S

Molecular Weight

597.65

Smiles

C(NS(=O)(=O)C1=CN(C)N=C1C)(=O)C2=C(N=C(C=C2)N3N=C(OCC(C(F)(F)F)(C)C)C=C3)N4C[C@@H](C)CC4(C)C

Relative Density

1.38 (Predicted)

Purity

0.9987

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