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Dolutegravir sodium

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Cat Number

API1051375199

CAS Number

1051375-19-9

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Product Detail

CAS Number

1051375-19-9

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

Molecular Formula

C20H18F2N3NaO5

Molecular Weight

441.36

Smiles

[Na+].C[C@@H]1CCO[C@H]2CN3CC(C(=O)NCC4CCC(F)CC4F)C(=O)C([O-])C3C(=O)N12

Purity

0.9974

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