Dextroamphetamine Adipate

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Cat Number

API64770521

CAS Number

64770-52-1

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Product Detail Description Customer Q&A

CAS Number

64770-52-1

Synonyms

D-amphetamine adipate

Molecular Formula

C15H23NO4

Molecular Weight

281.35

Smiles

C[C@@H](CC1=CC=CC=C1)N.C(CCC(=O)O)CC(=O)O

General Description

Dextroamphetamine Adipate is the adipate salt of the dextrorotatory isomer of amphetamine, classified as a central nervous system stimulant. The dextro isomer produces stronger central stimulant effects with fewer peripheral cardiovascular effects.

Mechanism of Action

Dextroamphetamine promotes release of dopamine and norepinephrine from presynaptic storage vesicles and inhibits their reuptake, increasing catecholamine concentrations in the prefrontal cortex, enhancing attention, focus, and wakefulness.

Application

Used in the treatment of attention deficit hyperactivity disorder and narcolepsy. Dextroamphetamine Adipate is indicated for ADHD in children and adults, and for managing excessive daytime sleepiness in narcolepsy.

Why is the dextrorotatory isomer preferred over racemic amphetamine?

The dextro isomer provides more potent central stimulant effects on attention and focus while producing fewer peripheral cardiovascular side effects than the racemic mixture.