APIs

DBCO-PEG4-VC-PAB

Cat Number
CHE-0062

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Description
DBCO-PEGn-VC-PAB is a cleavable PEG-containing ADC linker for the development of antibody-coupled drugs (ADCs). The Val-Cit can be specifically cleaved by histone B; the DBCO (dibenzocyclooctyne) moiety is typically used for copper-free click chemistry; and the hydrophilic PEG spacer group improves the water solubility of the compound.
Molecular Weight
914.1
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