Ceruletide Diethylamine

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Cat Number

API71247251

CAS Number

71247-25-1

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Product Detail Description Customer Q&A

CAS Number

71247-25-1

Molecular Formula

C62H84N14O21S2

Molecular Weight

1425.5

Smiles

CCNCC.C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]5CCC(=O)N5)O

General Description

Ceruletide Diethylamine is a synthetic decapeptide analog of the gastrointestinal hormone cholecystokinin. It stimulates gallbladder contraction and pancreatic enzyme secretion.

Mechanism of Action

Ceruletide agonizes cholecystokinin A receptors in the gallbladder and pancreas, stimulating gallbladder smooth muscle contraction and relaxation of the sphincter of Oddi while promoting pancreatic enzyme and bicarbonate secretion.

Application

Used in diagnostic evaluation of gallbladder and pancreatic function. Ceruletide Diethylamine is indicated for cholecystography, pancreatic function testing, and treatment of postoperative intestinal atony.

What diagnostic advantage does Ceruletide offer over natural cholecystokinin?

Ceruletide is a synthetic peptide with longer duration and improved stability compared to natural cholecystokinin, enabling reliable diagnostic assessment of gallbladder function.