CBZ-L-ALANINOL

Inquiry

Cat Number

INT66674166

CAS Number

66674-16-6

If you have any other questions, please contact our experts.

Product Detail Description Customer Q&A

CAS Number

66674-16-6

EINECS

822-974-3

Storage

Store at room temperature

Synonyms

(S)-(2-HYDROXY-1-METHYLETHYL)CARBAMIC ACID BENZYL ESTER;(S)-(-)-2-(Z-AMINO)-1-PROPANOL;N-CARBOBENZOXY-L-ALANINOL;N-Z-L-ALANINOL

Molecular Formula

C11H15NO3

Molecular Weight

209.24

Smiles

C[C@@H](CO)NC(=O)OCC1=CC=CC=C1

Appearance

White to off-white solid

Melting Point

81-84℃

Boiling Point

375.2℃

Relative Density

1.15

pKa

11.9

General Description

CBZ-L-ALANINOL is a protected amino alcohol derived from L-alanine. The substitution of the carboxyl group for a primary alcohol significantly changes its synthetic utility.

Mechanism of Action

It acts as a chiral precursor for amino aldehydes or reactive halides. The Cbz group protects the nitrogen while the alcohol group can be converted into various electrophilic or nucleophilic centers.

Application

It is a vital intermediate in the synthesis of HIV protease inhibitors and other bioactive molecules featuring chiral amino alcohol motifs.