CBZ-ASP(OBZL)-OBZL

Inquiry

Cat Number

INT5241601

CAS Number

5241-60-1

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Product Detail Description Customer Q&A

CAS Number

5241-60-1

Storage

2-8℃

Synonyms

Z-L-ASPARTIC ACID DIBENZYL ESTER;Z-ASP(OBZL)-OBZL

Molecular Formula

C26H25NO6

Molecular Weight

447.48

Smiles

C1=CC=C(C=C1)COC(=O)C[C@@H](C(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

Melting Point

64℃

Boiling Point

611.7℃

Relative Density

1.23

pKa

10.39

General Description

CBZ-ASP(OBZL)-OBZL is a fully protected aspartic acid derivative featuring a carbobenzyloxy group on the amino terminus and benzyl esters on both the alpha and side-chain carboxyl groups.

Mechanism of Action

It serves as a tri-protected building block where all functional groups are masked by benzyl-based protectors. This allows for total global deprotection via a single catalytic hydrogenation step, ensuring the integrity of the peptide backbone.

Application

It is primarily used in solution-phase peptide synthesis for the construction of complex peptide sequences and as a precursor for specific aspartyl-based diagnostic agents.