CBZ-ASP(OBZL)-OBZL

CBZ-ASP(OBZL)-OBZL

Cat Number
INT5241601
CAS Number
5241-60-1

If you have any other questions, please contact our experts.

CAS Number
5241-60-1
Storage
2-8℃
Synonyms
Z-L-ASPARTIC ACID DIBENZYL ESTER;Z-ASP(OBZL)-OBZL
Molecular Formula
C26H25NO6
Molecular Weight
447.48
Smiles
C1=CC=C(C=C1)COC(=O)C[C@@H](C(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3
Melting Point
64℃
Boiling Point
611.7℃
Relative Density
1.23
pKa
10.39
General Description
CBZ-ASP(OBZL)-OBZL is a fully protected aspartic acid derivative featuring a carbobenzyloxy group on the amino terminus and benzyl esters on both the alpha and side-chain carboxyl groups.
Mechanism of Action
It serves as a tri-protected building block where all functional groups are masked by benzyl-based protectors. This allows for total global deprotection via a single catalytic hydrogenation step, ensuring the integrity of the peptide backbone.
Application
It is primarily used in solution-phase peptide synthesis for the construction of complex peptide sequences and as a precursor for specific aspartyl-based diagnostic agents.

How should CBZ-ASP(OBZL)-OBZL be stored?

It should be kept in a cool, dry place in a tightly sealed container.

Is CBZ-ASP(OBZL)-OBZL soluble in organic solvents?

Yes, it shows excellent solubility in common solvents like dichloromethane and ethyl acetate.

Does CBZ-ASP(OBZL)-OBZL meet industry standards?

Yes, its production is compliant with international industry standards.

Are COAs provided for CBZ-ASP(OBZL)-OBZL?

Yes, every batch of it includes a detailed Certificate of Analysis.

What is the primary role of CBZ-ASP(OBZL)-OBZL?

It acts as a protected intermediate for large-scale peptide synthesis.
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