Bruceine A

Inquiry

Cat Number

PIPE-0628

CAS Number

25514-31-2

If you have any other questions, please contact our experts.

Product Detail

CAS Number

25514-31-2

Storage

Room temperature

Synonyms

BRUCEIN A methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-10,15,16-trihydroxy-9,13-dimethyl-3-(3-methylbutanoyloxy)-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate Isobruceine A

Description

Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection.

Molecular Formula

C26H34O11

Molecular Weight

522.5

Appearance

Powder

Purity

HPLC≥60%

You Might Also Like