BOC-TYR(ET)-OH

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Cat Number

INT76757910

CAS Number

76757-91-0

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Product Detail Description Customer Q&A

CAS Number

76757-91-0

Storage

2-8℃

Synonyms

N-(TERT-BUTOXYCARBONYL)-O-ETHYLTYROSINE;(2S)-3-(4-ethoxyphenyl)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid;N-ALPHA-T-BOC-O-ETHYL-L-TYROSINE

Molecular Formula

C16H23NO5

Molecular Weight

309.36

Appearance

White to off-white solid

General Description

BOC-TYR(ET)-OH is a protected L-tyrosine derivative featuring a Boc-protected alpha-amine and an ethyl ether modification on the phenolic oxygen. This modification renders the tyrosine residue more hydrophobic than its methyl-ether or hydroxyl counterparts.

Mechanism of Action

It acts as a stable, side-chain protected monomer for peptide assembly. The ethyl ether group effectively masks the phenol reactivity, ensuring that only the carboxylic acid participates in peptide bond formation, while the Boc group remains available for selective removal.

Application

It is used in the synthesis of non-natural peptides and biological probes where an ethoxylated tyrosine residue is required to modulate the physical or biological properties of the target molecule.