Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

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Cat Number

INT486460008

CAS Number

486460-00-8

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Product Detail

CAS Number

486460-00-8

EINECS

691-120-8

Storage

2-8℃

Synonyms

Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-;(R)-Sitagliptin N-Boc-Acid IMpurity;(3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;(3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)butanoic acid (BOC acid);[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta

Description

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid is used in the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as Sitagliptin.

Molecular Formula

C15H18F3NO4

Molecular Weight

333.31

Appearance

White solid

Melting Point

136-138℃

Boiling Point

443.1±45.0 ℃(Predicted)

Relative Density

1.292±0.06