BOC-MET-OL

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Cat Number

INT51372931

CAS Number

51372-93-1

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Product Detail Description Customer Q&A

CAS Number

51372-93-1

Storage

2-8℃

Synonyms

N-ALPHA-T-BOC-L-METHIONINOL;N-BOC-L-METHIONINOL;N-(TERT-BUTOXYBUTOXYCARBONYL)-L-METHIONINOL;N-T-BUTOXYCARBONYL-L-METHIONINOL;BOC-L-METHIONINOL

Molecular Formula

C10H21NO3S

Molecular Weight

235.34

Smiles

CSCC[C@@H](CO)NC(=O)OC(C)(C)C

Appearance

White to off-white solid

Melting Point

48.0 to 52.0℃

General Description

BOC-MET-OL (Boc-L-methioninol) is a reduced analog of L-methionine where the C-terminal carboxylic acid has been transformed into a primary alcohol. This molecule retains the thioether side chain and the protected amino group.

Mechanism of Action

It serves as a chiral building block for the synthesis of methionine-derived pharmaceuticals. The terminal alcohol group provides a versatile handle for etherification, esterification, or further oxidation to an aldehyde for subsequent reductive amination reactions.

Application

It is primarily used in the development of enzyme inhibitors, particularly those targeting methionine-dependent signaling, and in the synthesis of complex chiral intermediates for drug discovery.