Benzyl Benzoate

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Cat Number

PIVE-0005

CAS Number

120-51-4

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Product Detail Description Customer Q&A

CAS Number

120-51-4

EINECS

204-402-9

Storage

Store at room temperature

Synonyms

Ascabiol; Benzoic acid, phenylmethyl ester; Benylate; Benzoic acid, benzyl ester; Novoscabin; Scobenol; Phenylmethyl benzoate; Ascabin

Molecular Formula

C14H12O2

Molecular Weight

212.24

Smiles

C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2

Appearance

Colourless oily liquid with pleasant aromatic odour

Melting Point

18°C

Boiling Point

323-324°C

Relative Density

1.118

General Description

Benzyl benzoate is an organic compound formed by the esterification of benzyl alcohol and benzoic acid, with the chemical formula C₆H₅COOCH₂C₆H₅. It is a clear, colorless, oily liquid with a faint, sweet, balsamic odor, practically insoluble in water but miscible with alcohol and oils. Benzyl benzoate is a white to pale yellow crystalline solid at room temperature.

Mechanism of Action

Benzyl benzoate acts as a scabicidal agent by penetrating the chitinous exoskeleton of the mite Sarcoptes scabiei, disrupting its nervous system and causing paralysis and death. The exact mechanism is not fully understood, but it is believed to interfere with the mite's sodium channels or inhibit respiratory enzymes. The drug also has a mild local anesthetic effect, reducing itching.

Application

Benzyl benzoate is indicated as a topical treatment for scabies (infestation with Sarcoptes scabiei), particularly in resource-limited settings or for patients with contraindications to permethrin. It is also used as a pediculicide for head lice and as a topical antipruritic agent. The drug is less effective than permethrin but is still considered a second-line treatment for scabies.

Does Benzyl Benzoate require protection from light and heat during storage?

Yes, it is sensitive to light and heat, which can cause oxidation and discoloration. Store in light-resistant, tightly sealed containers at controlled room temperature (15-25°C).