ALYFTREK®

Drug Information Related Patent
Hold Company
VERTEX PHARMS INC
Dosage and Administration
TABLET;ORAL
Specification
50MG 20MG EQ 4MG BASE; 125MG 50MG EQ 10MG BASE
Indication
Alyftrek® is indicated for the treatment of cystic fibrosis (CF) in patients 6 years of age and older who have at least one F508del mutation or another responsive mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene
API
DEUTIVACAFTOR; TEZACAFTOR; VANZACAFTOR CALCIUM
API Structure
Drug Patent
Patent NoExpiration Date
100223522027/4/9
100470532032/5/17
100816212031/3/25
102398672027/4/9
106464812029/8/13
110664172039/2/14
115649162029/8/13
115780622031/3/25
116393472027/4/9
118664502039/2/14
118733002040/8/13
74951032027/5/20
76457892027/5/1
77769052027/6/3
83242422027/8/5
83544272026/7/6
84102742026/12/28
84153872027/11/12
85981812027/5/1
86239052027/5/1
86291622025/6/24
87542242026/12/28
88659022032/5/17
91811922032/5/17
95120792032/5/17
96701632026/12/28
99313342026/12/28
99747812027/4/9
API Patent
Patent NoExpiration Date
100223522027/4/9
100470532032/5/17
102398672027/4/9
110664172039/2/14
116393472027/4/9
118664502039/2/14
74951032027/5/20
76457892027/5/1
77769052027/6/3
83242422027/8/5
83544272026/7/6
84153872027/11/12
85981812027/5/1
86239052027/5/1
88659022032/5/17
91811922032/5/17
95120792032/5/17
99747812027/4/9

Note: The patent information provided herein is derived solely from publicly available data in the FDA Orange Book (or other cited sources) and is presented for general informational purposes only. Actual patent status may vary based on jurisdictional rulings, regulatory extensions or other factors.

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