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8-hydroxy Efavirenz

8-hydroxy Efavirenz

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Cat Number
API205754332
CAS Number
205754-33-2

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CAS Number
205754-33-2
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Description
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.
Molecular Formula
C14H9ClF3NO3
Molecular Weight
331.68
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