7-Ethyl-10-hydroxycamptothecin

Inquiry

Cat Number

PIPE-0747

CAS Number

86639-52-3

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Product Detail

CAS Number

86639-52-3

EINECS

643-093-9

Storage

Room temperature

Synonyms

7-Ethyl-10-hydroxycamptothecin SN 38 SN 38 lactone

Description

7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others.

Molecular Formula

C22H20N2O5

Molecular Weight

392.4

Appearance

Pale Yellow to Light Yellow Solid

Melting Point

>169℃ (dec.)

Boiling Point

810.3±65.0℃ (Predicted)

Purity

0.98