4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

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Cat Number

INT3680691

CAS Number

3680-69-1

For research use only. We do not supply to patients.

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Product Detail

CAS Number

3680-69-1

Storage

Keep in dark place,Inert atmosphere, 2-8 ℃

Synonyms

4-CHLORO-1H-PYRROLO(2,3-D)PYRIMIDINE;4-CHLOROPYRROLO[2,3-D]PYRIMIDINE;4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE;6-CHLORO-7-DEAZAPURINE;6-CHLORO-7-DEAZAPURINE 4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE 4-CHLORO-1H-PYRROLO[2,3-D]PYRIMIDINE 4-CHLOROPYRROLO[2,3-D]PYRIMIDINE 6-CHLORO-7-DEAZAPURIN;4-Chloro-1H-pyrrolo[2,3-d]pyrimidine4-Chloropyrrolo[2,3-d]pyrimidine;6-Chloro-7-deazapurin;4-CHLORO-4H-PYRROLO[2,3-D]PYRIMIDINE

Description

4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is an important pharmaceutical intermediate. Also, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is the intermediate of the bulk drug, Tofatinib, which was widely used in treatment of adult patients with moderate to severe rheumatoid arthritis with inadequate or intolerant methotrexate response.

Molecular Formula

C6H4ClN3

Molecular Weight

153.57

Appearance

Crystalline Powder

Melting Point

188-194 ℃

Boiling Point

289.2±50.0 ℃(Predicted)

Color

White to tan