3,4`,5-Trimethoxy-trans-stilbene

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Cat Number

PIPE-0648

CAS Number

22255-22-7

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Product Detail

CAS Number

22255-22-7

EINECS

694-659-7

Storage

Room temperature

Synonyms

trans-Trimethoxyresveratrol (E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene (E)-3,5,4'-Trimethoxystilbene

Description

3,4',5-Trimethoxystilbene is isolated from the herbs of Virola cuspidata. 3,4',5-Trimethoxystilbene exerts antiallergic and anti-mitotic properties. It shows antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation. 3,4',5-Trimethoxystilbene is a potent small molecule inducer of autophagy in human umbilical vascular endothelial cells (HUVECs) in the presence of serum. It has anti-inflammatory activity, the ability of it to induce HO-1 expression may provide one of possible mechanisms of its anti-inflammatory action. 3,4',5-Trimethoxystilbene shows potent antitumor and anti-HCV activities without exhibiting cytotoxicity to human hepatocytes in vitro or in mice livers. It acts as an inhibitor of tubulin polymerization.

Molecular Formula

C17H18O3

Molecular Weight

270.32

Appearance

Powder

Melting Point

57℃

Boiling Point

423.8±35.0 ℃(Predicted)

Purity

HPLC≥98%