3,4-Dichloroaniline-6-sulfonic acid

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Cat Number

INT6331960

CAS Number

6331-96-0

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Product Detail Description Customer Q&A

CAS Number

6331-96-0

EINECS

700-413-2

Storage

Room temperature

Synonyms

2-amino-4,5-dichlorobenzenesulphonic acid;4,5-Dichloroorthanilic acid

Molecular Formula

C6H5Cl2NO3S

Molecular Weight

242.08

Appearance

White to off-white solid

Relative Density

1.75

pKa

0.76

General Description

3,4-Dichloroaniline-6-sulfonic acid is a polyhalogenated aniline bearing both chlorine atoms at the 3- and 4-positions and a sulfonic acid group at the 6-position of the benzene ring. The sulfonic acid provides water solubility and confers acidic properties, while the dichloro substitution imparts electronic and steric effects that modify the amine's nucleophilicity and oxidation resistance. This compound is primarily used as a functionalized intermediate in azo dye and pharmaceutical synthesis.

Mechanism of Action

3,4-Dichloroaniline-6-sulfonic acid functions as a diazotizable aromatic amine suitable for conversion to diazonium salts, which can subsequently undergo Sandmeyer-type reactions (to introduce halides, cyano, hydroxyl) or azo coupling reactions with electron-rich aromatic partners to form azo dyes and pigments. The sulfonic acid group activates the ring for electrophilic substitution and enhances water solubility of resulting products.

Application

3,4-Dichloroaniline-6-sulfonic acid is used as an intermediate in the synthesis of azo dyes, pharmaceuticals, and agrochemicals. The dichloro substitution pattern provides resistance to oxidative metabolism in pharmaceutical applications where metabolic stability is critical. It is used in the synthesis of chlorinated aromatic compounds including anti-infective agents and UV-absorbing materials.

What is the recommended storage condition for 3,4-Dichloroaniline-6-sulfonic acid?

It should be stored at controlled room temperature in a well-sealed container, protected from moisture and direct light, to maintain its chemical integrity throughout the shelf life.

Can we obtain batch-specific analytical data for 3,4-Dichloroaniline-6-sulfonic acid?

Batch-specific COA documents are standard with every shipment. Additional analytical reports, including HPLC chromatograms or spectral data, may be provided upon request.

What is the primary synthetic application of 3,4-Dichloroaniline-6-sulfonic acid?

It is widely used as a key building block or intermediate in multi-step pharmaceutical synthesis workflows, providing versatile reactivity for constructing target molecular architectures.

Can 3,4-Dichloroaniline-6-sulfonic acid be provided with custom specifications for synthetic applications?

Custom specifications including adjusted particle size, solvent residue limits, or additional purity testing can be arranged for qualified customers with defined requirements.

Does your company offer custom packaging for 3,4-Dichloroaniline-6-sulfonic acid?

Yes, custom pack sizes are available. Specific quantity requirements can be discussed directly with our team to align with your production or research scale.