3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Inquiry

Cat Number

INT151266238

CAS Number

151266-23-8

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Product Detail

CAS Number

151266-23-8

Storage

Keep in dark place, sealed in dry, room temperature

Synonyms

3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE;4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE;4-Amino-3-iodopyrazolo[3,4-d]pyrimidine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-;4-Amino-3-iodo-1H-pyrazolo[3,4-D]pyridine;3-iodo-4-AMino-1H-pyrazolo[3,4-d]pyridine;7-Iodo-7-deaza-8-aza-adenine

Description

3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.

Molecular Formula

C5H4IN5

Molecular Weight

261.02

Appearance

powder to Crystal

Boiling Point

312.3±52.0 ℃(Predicted)

Color

White to Light yellow to Light orange

pKa

10.50±0.20(Predicted)