3-Chloro-2-pryazine-carboxylic acid

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Cat Number

INT27398396

CAS Number

27398-39-6

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Product Detail

CAS Number

27398-39-6

Storage

Under inert gas (nitrogen or Argon) at 2-8 ℃

Synonyms

RARECHEM AL BO 0855;3-CHLORO-2-PYRAZINE-CARBOXYLIC ACID;3-CHLORO-PYRAZINE-2-CARBOXYLIC ACID;3-Chloro-2-pyrazine-carboxylic a;3-Chloropyrazine-2-corboxylic acid;2-Pyrazinecarboxylic acid, 3-chloro-

Description

3-Chloro-2-pryazine-carboxylic acid is used in the synthesis of a novel inhibitor (CX-4945) of protein kinase CK2 in the treatment of cancer. 3-Chloro-2-pryazine-carboxylic acid can be used in the synthesis of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.

Molecular Formula

C5H3ClN2O2

Molecular Weight

158.54

Melting Point

116-117 ℃ (decomp)

Boiling Point

317.0±37.0 ℃(Predicted)

pKa

1.51±0.25(Predicted)

Purity

0.97