2-Me-D-Trp-OH

2-Me-D-Trp-OH

Cat Number
INT140852068
CAS Number
140852-06-8

If you have any other questions, please contact our experts.

CAS Number
140852-06-8
Storage
Store at room temperature
Synonyms
D-Tryptophan 2-methyl-;(2R)-2-amino-3-(2-methyl-1H-indol-3-yl)propanoic acid;(R)-2-Amino-3-(2-methyl-1H-indol-3-yl)propanoic acid
Molecular Formula
C12H14N2O2
Molecular Weight
218.25
Smiles
CC1=C(C2=CC=CC=C2N1)C[C@H](C(=O)O)N
Appearance
White to off-white solid
Boiling Point
452.8℃
Relative Density
1.31
pKa
2.26
General Description
2-Me-D-Trp-OH is a methylated derivative of D-tryptophan where a methyl group is substituted at the 2-position of the indole ring, modifying the electronic and steric properties of the heterocycle.
Mechanism of Action
It functions as a constrained indole building block. The 2-methyl group increases the lipophilicity of the amino acid and can interfere with the binding of enzymes that typically metabolize tryptophan, such as indoleamine 2,3-dioxygenase (IDO).
Application
It is utilized in the development of novel immunotherapeutic agents and as a chiral intermediate for the synthesis of complex indole alkaloids.

How to store 2-Me-D-Trp-OH?

It should be kept in a cool, dark place away from oxidizing agents.

Is 2-Me-D-Trp-OH a chiral molecule?

Yes, it is the D-enantiomer with high optical purity.

Does 2-Me-D-Trp-OH meet industry standards?

Yes, its production is compliant with international industry standards.

Are COAs provided for 2-Me-D-Trp-OH?

Yes, a batch-specific COA is provided with it for every shipment.

Can 2-Me-D-Trp-OH be used in research?

Yes, it is a high-purity intermediate for pharmaceutical and biochemical R&D.
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