2-[3-Chloro-5-(trifluoroMethyl)-2-pyridinyl]-acetonitrile

Inquiry

Cat Number

INT157764108

CAS Number

157764-10-8

If you have any other questions, please contact our experts.

Product Detail Description Customer Q&A

CAS Number

157764-10-8

Storage

2-8℃

Synonyms

3-Chloro-2-(cyanomethyl)-5-(trifluoromethyl)pyridine;2-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]acetonitrile;2-Pyridineacetonitrile, 3-chloro-5-(trifluoromethyl)-

Molecular Formula

C8H4ClF3N2

Molecular Weight

220.58

Smiles

C1=C(C=NC(=C1Cl)CC#N)C(F)(F)F

Appearance

Off-white to yellow solid

Boiling Point

245.7℃

Relative Density

1.429

General Description

2-[3-Chloro-5-(trifluoroMethyl)-2-pyridinyl]-acetonitrile is a highly functionalized pyridine derivative featuring a chlorine atom, a trifluoromethyl group, and an acetonitrile moiety. The combination of these electron-withdrawing groups results in a uniquely reactive aryl system used for specialized chemical transformations.

Mechanism of Action

It serves as a functionalized aryl building block where the acetonitrile group acts as a versatile precursor for conversion into amines, carboxylic acids, or heterocyclic rings. The trifluoromethyl group significantly enhances the lipophilicity and metabolic stability of the resulting molecules.

Application

It is a key intermediate for synthesizing various pharmaceutical APIs and specialized chemical reagents, particularly in the fields of cardiovascular and anti-infective research.