1-Boc-3-azetidinone

1-Boc-3-azetidinone

Cat Number
INT398489264
CAS Number
398489-26-4

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

CAS Number
398489-26-4
EINECS
627-725-0
Storage
2-8℃
Synonyms
tert-Butyl 3-oxoazetidine-1-carboxylate, 3-Oxoazetidine;N-(t-butoxycarbonyl)azetidin-3-one;tert-Butyl 3-oxoazetidine-1-carboxylat
Molecular Formula
C8H13NO3
Molecular Weight
171.19
Smiles
N1(C(OC(C)(C)C)=O)CC(=O)C1
Appearance
White to off-white powder
Melting Point
47-51℃
Boiling Point
251.3℃
Relative Density
1.174
General Description
1-Boc-3-azetidinone is a Boc-protected four-membered cyclic ketone. It is a highly valued reagent in modern medicinal chemistry.
Mechanism of Action
It acts as a versatile electrophile. The ketone group allows for reactions such as reductive amination, Grignard addition, or olefination to produce 3-substituted azetidine derivatives with specific structural features.
Application
It is extensively used in the synthesis of complex pharmaceutical candidates and specialized chemical libraries targeting various therapeutic areas.

How to store 1-Boc-3-azetidinone?

It should be stored in a cool, dry place away from acidic conditions.

Is 1-Boc-3-azetidinone reactive?

Yes, the ketone group in it is a versatile site for chemical transformations.

Are SDS available for 1-Boc-3-azetidinone?

Yes, we provide a comprehensive SDS for it upon request.

Is global shipping available for 1-Boc-3-azetidinone?

Yes, we ship it internationally in specialized packaging.

What is the primary role of 1-Boc-3-azetidinone?

It acts as a key building block for constructing 3-substituted azetidines.
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