1-Boc-3-azetidinone

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Cat Number

INT398489264

CAS Number

398489-26-4

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Product Detail Description Customer Q&A

CAS Number

398489-26-4

EINECS

627-725-0

Storage

2-8℃

Synonyms

tert-Butyl 3-oxoazetidine-1-carboxylate, 3-Oxoazetidine;N-(t-butoxycarbonyl)azetidin-3-one;tert-Butyl 3-oxoazetidine-1-carboxylat

Molecular Formula

C8H13NO3

Molecular Weight

171.19

Smiles

N1(C(OC(C)(C)C)=O)CC(=O)C1

Appearance

White to off-white powder

Melting Point

47-51℃

Boiling Point

251.3℃

Relative Density

1.174

General Description

1-Boc-3-azetidinone is a Boc-protected four-membered cyclic ketone. It is a highly valued reagent in modern medicinal chemistry.

Mechanism of Action

It acts as a versatile electrophile. The ketone group allows for reactions such as reductive amination, Grignard addition, or olefination to produce 3-substituted azetidine derivatives with specific structural features.

Application

It is extensively used in the synthesis of complex pharmaceutical candidates and specialized chemical libraries targeting various therapeutic areas.

How to store 1-Boc-3-azetidinone?

It should be stored in a cool, dry place away from acidic conditions.

Is 1-Boc-3-azetidinone reactive?

Yes, the ketone group in it is a versatile site for chemical transformations.

Are SDS available for 1-Boc-3-azetidinone?

Yes, we provide a comprehensive SDS for it upon request.

Is global shipping available for 1-Boc-3-azetidinone?

Yes, we ship it internationally in specialized packaging.

What is the primary role of 1-Boc-3-azetidinone?

It acts as a key building block for constructing 3-substituted azetidines.

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