Magnesium Chloride

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Cat Number

PIVF-0064

CAS Number

7786-30-3

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

Product Detail Description Advanced Innovations Customer Q&A

CAS Number

7786-30-3

EINECS

232-094-6

Storage

2-8℃

Molecular Formula

Cl2Mg

Molecular Weight

95.21

Smiles

Cl[Mg]Cl

Appearance

White powder

Melting Point

714 ℃

Boiling Point

1412 ℃

Relative Density

2.32

General Description

Magnesium Chloride is an inorganic salt that is extremely deliquescent. It is used both in biology and manufacturing processes as an important source of magnesium ions. It is commonly used as a reagent in molecular biology, clinical medicine and organic chemistry synthesis.

Mechanism of Action

Biologically magnesium ions serve as cofactors for hundreds of enzyme reactions, including those utilizing ATP, DNA, and RNA. During DNA synthesis, it binds to the phosphate groups of nucleotides and stabilizes the transition state of the phosphodiester bond-forming reaction, thus activating polymerases. Magnesium Chloride can also influence neuromuscular excitability under physiological conditions, blocking calcium influx through voltage-dependent calcium channels and reducing neurotransmitter release.

Application

Magnesium Chloride can be used industrially as a precursor to magnesium metal, a coagulant in food manufacturing and as an effective de-icing agent. Additionally MgCl2 has been used as an electrolyte replenisher and pharmaceutical stabilizer.

Four different gelatin/alginate based scaffolds modified with HAp and second modifier hydrated magnesium chloride (two concentrations: 1.90% and 2.88%), ZnO and nHAp were prepared by the two-step freeze-drying process. Hydrogels had a gradient hierarchical porosity with low surface porosity and high porosity towards the center similar to natural cartilage.
Variation of magnesium chloride did not show any statistically significant impact on permeability; however, scaffolds with higher concentrations of MgCl₂ showed larger pore sizes (up to 1430 μm) and decreased mechanical strength as compared to lower MgCl₂ concentration (1.90%). Addition of ZnO resulted in scaffolds with the highest permeability and mechanical performance while scaffolds modified with nHAp displayed the lowest permeability. MgCl₂ scaffolds with lower magnesium content displayed better mechanical properties.

Fig. 1 Preparation of zinc oxide and Magnesium Chloride-modified hydrogel scaffolds. (de Mello Innocentini M D.; et al. 2024)

References

de Mello Innocentini M D.; et al. Microstructural, Fluid Dynamic, and Mechanical Characterization of Zinc Oxide and Magnesium Chloride-Modified Hydrogel Scaffolds. ACS Biomaterials Science & Engineering, 2024, 10(8): 4791-4801.

Under what conditions should magnesium chloride be stored?

Store containers tightly closed in a dry place.

What is your minimum order quantity?

It will vary based on the grade/package size.

Is Magnesium Chloride soluble in organic solvents?

Magnesium Chloride is water-soluble. Also dissolves easily in ethanol or methanol. Sparingly soluble in non-polar organic solvents.

Can MgCl2 be used as a joint supplement for animals?

Yes. MgCl2 has natural anti-inflammatory effects which can help alleviate joint inflammation and pain.