β-Estradiol

β-Estradiol

Cat Number
PIPE-0767
CAS Number
50-28-2

For research use only. We do not supply to patients.

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CAS Number
50-28-2
EINECS
200-023-8
Storage
Room temperature
Synonyms
estradiol beta-Estradiol 17beta-Estradiol Oestradiol
Description
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams. When used for oral or IM administration, estradiol is commonly synthesized as a pro-drug ester (such as [DB13952], [DB13953], [DB13954], [DB13955], and [DB13956]). Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.
Molecular Formula
C18H24O2
Molecular Weight
272.4
Appearance
White powder.
Melting Point
178-179 ℃
Boiling Point
445.9±45.0
Purity
HPLC≥98%
Applications
human sex hormone
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