Cat Number: API70008

TrifluridineNSC 529182, Trifluorothymidine, 5-Trifluorothymidine, NSC 75520, Viroptic, Trifluridina

APIs
CAS Number
70-00-8
Description
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.
Molecular Formula
C10H11F3N2O5
Molecular Weight
296.2
Smiles
O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(F)(F)F)C(=O)N1
Purity
0.9982
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
H2O: 14.8 mg/mL (50 mM)DMSO: 55 mg/mL (185.69 mM), Sonication is recommended.
Relative Density
1.646
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