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Cat Number: API1187431431

Trametinib (DMSO solvate)Trametinib DMSO solvate, GSK-1120212 (DMSO solvate), Trametinib dimethyl sulfoxide, JTP-74057 (DMSO solvate)

CAS Number

1187431-43-1

Description

Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and selective MEK inhibitor that specifically inhibits MEK1/2 (IC50: 2 nM).

Molecular Formula

C28H29FIN5O5S

Molecular Weight

693.53

Smiles

CS(C)=O.CC(=O)NC1CCCC(C1)-N1C2C(C)C(=O)N(C)C(NC3CCC(I)CC3F)C2C(=O)N(C2CC2)C1=O

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 69 mg/mL (99.49 mM)

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