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Cat Number: API274693275

TicagrelorAR-C 126532XX, AZD6140

CAS Number

274693-27-5

Description

Ticagrelor (AR-C 126532XX), produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European Union by the European Commission on December 3, 2010, and by the US FDA on July 20, 2011. Its trade names are Brilinta (US), Brilique(EU) and Possia(EU).

Molecular Formula

C23H28F2N6O4S

Molecular Weight

522.57

Smiles

CCCSC1NC(N[C@@H]2C[C@H]2C2CCC(F)C(F)C2)C2NNN([C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)C2N1

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (95.68 mM)5% DMSO+40 % PEG300+5 % Tween 80+50 % Saline: 5 mg/mL (9.57 mM), In vivo: Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately.

Relative Density

1.67

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