An ISO9001 Certified Supplier of Pharmaceutical Ingredients and Specialty Chemicals

Cat Number: API1505515694

TaletrectinibDS-6051b, AB-106

CAS Number

1505515-69-4

Description

Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.

Molecular Formula

C29H34FN5O5

Molecular Weight

551.61

Smiles

OC(=O)CCCCC(O)=O.C[C@@H](N)COC1CCC(CC1)-C1CNC2CCC(N[C@H](C)C3CCCC(F)C3)NN12

Purity

0.9996

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 45 mg/mL (81.58 mM)

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