Description
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.
Molecular Formula
C26H33FN4O7
Smiles
O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)C1C(C)[NH]C(\C=C2/C(=O)NC3CCC(F)CC23)C1C
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 6.25 mg/mL (11.74 mM), Sonication is recommended.