Description
Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C.
Molecular Formula
C22H29FN3O9P
Smiles
CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](N2CCC(=O)[NH]C2=O)[C@](C)(F)[C@@H]1O)OC1CCCCC1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
Ethanol: 93 mg/mL (175.7 mM)DMSO: 60 mg/mL (113.33 mM)H2O: 9 mg/mL (17 mM)