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Cat Number: API486460326

SitagliptinMK0431

CAS Number

486460-32-6

Description

Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus.

Molecular Formula

C16H15F6N5O

Molecular Weight

407.31

Smiles

N[C@@H](CC(=O)N1CCN2C(C1)NNC2C(F)(F)F)CC1CC(F)C(F)CC1F

Purity

0.994

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 16.67 mg/mL (40.92 mM)H2O: ＜1 mg/mL (Insoluble)