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Cat Number: API654671779

Sitagliptin phosphate monohydrateMK-0431, MK-0431 phosphate monohydrate

CAS Number

654671-77-9

Description

Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent DPP-IV inhibitor with an IC50 of 19 nM in Caco-2 cell extracts.

Molecular Formula

C16H15F6N5O·H3PO4·H2O

Molecular Weight

523.33

Smiles

OP(O)(O)=O.N[C@H](CC1=C(C=C(C(F)=C1)F)F)CC(N2CCN3C(C2)=NN=C3C(F)(F)F)=O.O

Purity

0.9965

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: 38 mg/mL (72.6 mM)Ethanol: < 1 mg/mL (insoluble or slightly soluble)DMSO: 93 mg/mL (177.7 mM)

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