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Cat Number: API943332089

Selumetinib sulfateAZD6244 sulfate, ARRY-142886 sulfate

CAS Number

943332-08-9

Description

Selumetinib sulfate (AZD6244 sulfate) is an orally available, selective and potent MEK1/2 inhibitor that inhibits MEK1/2 phosphorylation and may be useful for the study of symptomatic refractory fibroids in type 1 neurofibromatosis.

Molecular Formula

C17H17BrClFN4O7S

Molecular Weight

555.76

Smiles

O=C(NOCCO)C1=CC2=C(N=CN2C)C(F)=C1NC3=CC=C(Br)C=C3Cl.O=S(=O)(O)O

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: < 1 mg/mL (insoluble)DMSO: 40 mg/mL (71.97 mM), Sonication is recommended.

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