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Cat Number: API283173502

RucaparibAG-14447, PF-01367338, AG014699

CAS Number

283173-50-2

Description

Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC).

Molecular Formula

C19H18FN3O

Molecular Weight

323.36

Smiles

O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

Purity

0.9989

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 32.5 mg/mL (100.5 mM)