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Cat Number: API162401323

RoflumilastB9302-107, BYK 20869, APTA 2217, BY 217

CAS Number

162401-32-3

Description

Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities.

Molecular Formula

C17H14Cl2F2N2O3

Molecular Weight

403.21

Smiles

O(CC1CC1)C2=C(OC(F)F)C=CC(C(NC=3C(Cl)=CN=CC3Cl)=O)=C2

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)Ethanol: 12 mg/mL (29.8 mM)DMSO: 50 mg/mL (124 mM)

Relative Density

1.471 (Predicted)

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