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Cat Number: API926037481

RadotinibIY-5511, Supect

CAS Number

926037-48-1

Description

Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other tyrosine kinase Bcr-Abl inhibitors

Molecular Formula

C27H21F3N8O

Molecular Weight

530.5

Smiles

CC1CN(CN1)-C1CC(NC(=O)C2CCC(C)C(NC3NCCC(N3)-C3CNCCN3)C2)CC(C1)C(F)(F)F

Purity

0.9997

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)DMSO: 5.3 mg/mL (10 mM)