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Cat Number: API301692762

PolmacoxibCG-100649, CG100649, CG 100649

CAS Number

301692-76-2

Description

Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.

Molecular Formula

C18H16FNO4S

Molecular Weight

361.39

Smiles

CC1(C)OC(=C(C1=O)C1CCCC(F)C1)C1CCC(CC1)S(N)(=O)=O

Purity

0.9849

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: InsolubleDMSO: 55 mg/ml (152.19 mM)