Description
Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.
Molecular Formula
C50H46CaF2N2O8
Smiles
[Ca++].O[C@H](C[C@H](O)\C=C\C1C(NC2CCCCC2C1-C1CCC(F)CC1)C1CC1)CC([O-])=O.O[C@H](C[C@H](O)\C=C\C1C(NC2CCCCC2C1-C1CCC(F)CC1)C1CC1)CC([O-])=O
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 50 mg/mL (56.75 mM)