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Cat Number: API138786671

Pantoprazole sodiumPantecta, SKF96022 sodium, SKF96022 (sodium), BY1023 (sodium), BY-1023 sodium, Pantoloc

CAS Number

138786-67-1

Description

Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.

Molecular Formula

C16H14F2N3NaO4S

Molecular Weight

405.35

Smiles

[Na+].COC1CCNC(CS(=O)C2NC3CC(OC(F)F)CCC3[N-]2)C1OC

Purity

0.991

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 55 mg/mL (135.69 mM)H2O: 74 mg/mL (182.6 mM)Ethanol: 75 mg/mL (185 mM)