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Cat Number: API928134650

OsilodrostatLCI699

CAS Number

928134-65-0

Description

Osilodrostat (LCI699)is a potent inhibitor of human 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) with IC50 values of 2.5 and 0.7 nM, respectively, and has been approved by the FDA for the treatment of Cushing's disease.

Molecular Formula

C13H10FN3

Molecular Weight

227.24

Smiles

FC1CC(CCC1[C@H]1CCC2CNCN12)C#N

Purity

0.9912

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (220.03 mM)

Relative Density

1.32 (Predicted)

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