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Cat Number: API53230107

MefloquineWR 142490, Ro-215998, Ro215998, Ro 215998, Lariam

CAS Number

53230-10-7

Description

Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus, and cancer research.

Molecular Formula

C17H16F6N2O

Molecular Weight

378.31

Smiles

C(F)(F)(F)C=1C2=C(C([C@H](O)[C@]3(CCCCN3)[H])=CC(C(F)(F)F)=N2)C=CC1

Purity

0.9997

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 55 mg/ml (145.38 mM)