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Cat Number: API376348651

MaravirocCelsentri, UK-427857, Selzentry

CAS Number

376348-65-1

Description

Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.

Molecular Formula

C29H41F2N5O

Molecular Weight

513.67

Smiles

CC(C)C1NNC(C)N1[C@@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)C1CCCCC1

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 55 mg/mL (107.07 mM)Ethanol: 51.4 mg/mL (100 mM)

Relative Density

1.29 (Predicted)

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