An ISO9001 Certified Supplier of Pharmaceutical Ingredients and Specialty Chemicals

Cat Number: API936727058

LumacaftorVX-809, VRT 826809

CAS Number

936727-05-8

Description

Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).

Molecular Formula

C24H18F2N2O5

Molecular Weight

452.41

Smiles

CC1CCC(NC(=O)C2(CC2)C2CCC3OC(F)(F)OC3C2)NC1-C1CCCC(C1)C(O)=O

Purity

0.9972

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)Ethanol: 6 mg/mL (13.26 mM)DMSO: 50 mg/mL (110.52 mM)

Relative Density

1.517

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

Home
About Us
Products
Services
Contact Us

Tel:
E-mail:
Address:
WhatsAPP

Member of

CERTIFICATION