Description
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.
Molecular Formula
C17H20ClF2N3O3
Smiles
C1(NCCN(C1)C1C(CC2C(C1F)N(CC(C2=O)C(=O)O)CC)F)C.Cl
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
H2O: 10 mMDMSO: Insoluble