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Cat Number: API138199710

Levofloxacin hydrateLevaquin hydrate, Cravit hydrate, Quixin hydrate, Levofloxacin Hemihydrate, Tavanic hydrate, Iquix hydrate

CAS Number

138199-71-0

Description

Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

Molecular Formula

C18H20FN3O4·1/2H2O

Molecular Weight

370.38

Smiles

O.C[C@H]1COC2C(N3CCN(C)CC3)C(F)CC3C2N1CC(C(O)=O)C3=O.C[C@H]1COC2C(N3CCN(C)CC3)C(F)CC3C2N1CC(C(O)=O)C3=O

Purity

0.9856

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (135 mM), Sonication is recommended.H2O: 5 mg/mL (13.5 mM)Ethanol: 10 mg/mL (27 mM)Methanol: 10 mM