Description
Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.
Molecular Formula
C29H28F4N4O4
Smiles
COC1CCCC(C1)N1CCN(CC1)C1=NC2C(F)CCCC2[C@H](CC(O)=O)N1C1CC(CCC1OC)C(F)(F)F
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
Ethanol: 2 mg/mLDMSO: 70 mg/mL (122.26 mM)
Relative Density
1.37 (Predicted)