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Cat Number: API1223405080

Larotrectinib sulfateARRY-470 (sulfate), LOXO-101 sulfate, LOXO-101 (sulfate)

CAS Number

1223405-08-0

Description

Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).

Molecular Formula

C21H22F2N6O2·H2O4S

Molecular Weight

526.51

Smiles

OS(O)(=O)=O.O[C@H]1CCN(C1)C(=O)NC1CNN2CCC(NC12)N1CCC[C@@H]1C1CC(F)CCC1F

Purity

0.9969

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (94.96 mM)Ethanol: 10 mg/mL (19 mM)H2O: < 1 mg/mL (insoluble or slightly soluble)

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