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Cat Number: API388082777

Lapatinib DitosylateTykerb ditosylate, Lapatinib (GW-572016) Ditosylate, GW-572016 ditosylate

CAS Number

388082-77-7

Description

Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).

Molecular Formula

C29H26ClFN4O4S·2C7H8O3S

Molecular Weight

925.46

Smiles

CC1=CC=C(C=C1)S(O)(=O)=O.CC1=CC=C(C=C1)S(O)(=O)=O.CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(NC3=CC=C(OCC4=CC(F)=CC=C4)C(Cl)=C3)N=CN=C2C=C1

Purity

0.9971

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)DMSO: 93 mg/mL (100.5 mM)H2O: < 1 mg/mL (insoluble or slightly soluble)

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